Overview

Cancer of the sinuses (the air spaces in our face around the nose) is a rare and aggressive disease, which can be extensive by the time something is noticed to be wrong.

Treatment may involve surgery, radiotherapy and/or chemotherapy. Radiotherapy is an important part of treatment for this cancer and the current standard of care is Intensity-modulated radiotherapy (IMRT).

Proton beam therapy (PBT) is a newer form of therapy which may further improve the delivery of radiation.

PROTIS is designed to compare the current standard of care radiotherapy, IMRT, to PBT. The trial aims to find out which treatment is better at treating the cancer. The trial is also interested in understanding whether PBT causes fewer long-term side effects and results in a better quality of life after treatment.

Randomised patients

Target patients

276

Open sites

12

Target Sites

20

Key Contacts and Links

For further information about PROTIS, please contact:

Telephone


0151 794 9085

Address

Liverpool Clinical Trials Centre
Block C, Waterhouse Building
Brownlow Street
Liverpool
L69 3GL

 

Study Organiser

Liverpool Clinical Trials Centre (LCTC), part of University of Liverpool

The Christie NHS FT (sponsor)

Study review and approval

This study has been reviewed and approved within the UK by the Health Research Authority (HRA) and by London-Surrey Research Ethics Committee, who have agreed that the study is being conducted in a correct and appropriate manner.